Cardiol Res

Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access

Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc

Journal website https://www.cardiologyres.org

Original Article

Volume 2, Number 6, December 2011, pages 274-281

Systolic Strain Abnormalities to Predict Hospital Readmission in Patients With Heart Failure and Normal Ejection Fraction

**Table 1.** Baseline Demographics and Echocardiographic Parameters for Hospital Readmission for CHF
variable	Not readmitted for CHF (n = 48)	Readmitted for CHF (n = 52)	P value
^*values are statistically significant at P < 0.05.
Age (years)	76.17	77.55	0.602
Index length of stay (days)	4.88	5.35	0.481
Males (n, %)	13 (0.27)	21 (0.40)	0.206
Females (n, %)	35 (0.73)	31 (0.60)	0.206
Hypertension (n, %)	22 (0.45)	23 (0.44)	0.872
Diabetes (n, %)	16 (0.51)	26 (0.50)	0.154
BNP pg/mL	882	956	0.788
LVEF (%)	67	65	0.120
LVIDd (cm)	4.3	4.5	0.182
LVIDs (cm)	2.8	3.0	0.208
Septal thickness (cm)	1.2	1.3	0.084
Post wall thickness (cm)	1.12	1.20	0.360
LA dimension (cm)	4.2	4.1	0.704
Peak mitral E (cm/s)	97	93	0.520
E/a	1.6	1.4	0.236
E’ (cm/s)	8.5	7.7	0.263
E/e’	11.0	14.5	0.013*
Sa (cm/s)	7.7	7.5	0.619
Systolic strain (%)	-12.91	-11.74	0.198
Systolic strain rate (s^-1)	-1.09	-1.05	0.545

Table 1. Baseline Demographics and Echocardiographic Parameters for Hospital Readmission for CHF

variable

Not readmitted for CHF (n = 48)

Readmitted for CHF (n = 52)

P value

^*values are statistically significant at P < 0.05.

Age (years)

76.17

77.55

0.602

Index length of stay (days)

4.88

5.35

0.481

Males (n, %)

13 (0.27)

21 (0.40)

0.206

Females (n, %)

35 (0.73)

31 (0.60)

0.206

Hypertension (n, %)

22 (0.45)

23 (0.44)

0.872

Diabetes (n, %)

16 (0.51)

26 (0.50)

0.154

BNP pg/mL

882

956

0.788

LVEF (%)

0.120

LVIDd (cm)

4.3

4.5

0.182

LVIDs (cm)

2.8

3.0

0.208

Septal thickness (cm)

1.2

1.3

0.084

Post wall thickness (cm)

1.12

1.20

0.360

LA dimension (cm)

4.2

4.1

0.704

Peak mitral E (cm/s)

0.520

E/a

1.6

1.4

0.236

E’ (cm/s)

8.5

7.7

0.263

E/e’

11.0

14.5

0.013*

Sa (cm/s)

7.7

7.5

0.619

Systolic strain (%)

-12.91

-11.74

0.198

Systolic strain rate (s^-1)

-1.09

-1.05

0.545

**Table 2.** Baseline Demographics and Echocardiographic Parameters for All HFNEF Patients and Controls
Variable	HFNEF (n = 100)	Controls (n = 50)	P value
^*values are statistically significant at P < 0.05.
Age (years)	76	60	< 0.001*
Males (n, %)	34 (0.34)	32 (0.64)	< 0.001*
Females (n, %)	66 (0.66)	18 (0.36)	< 0.001*
Hypertension (n, %)	45 (0.45)	28 (0.54)	0.204
Diabetes (n, %)	42 (0.42)	10 (0.20)	0.007*
LVEF (%)	65	64	0.189
LVIDd (cm)	4.4	4.3	0.182
LVIDs (cm)	2.9	2.7	0.095
Septal thickness (cm)	1.25	1.14	0.003*
Post wall thickness (cm)	1.19	1.09	0.003*
LA dimension (cm)	4.1	3.4	< 0.001*
Peak mitral E (cm/s)	94	69	< 0.001*
E/a	1.5	1.0	< 0.001*
e’ (cm/s)	8.0	9.0	0.069
E/e’	12.9	8.3	< 0.001*
Sa (cm/s)	7.5	9.7	< 0.001*
Systolic strain (%)	-12.3	-15.4	< 0.001*
Systolic strain rate (s^-1)	-1.07	-1.07	0.957

Table 2. Baseline Demographics and Echocardiographic Parameters for All HFNEF Patients and Controls

Variable

HFNEF (n = 100)

Controls (n = 50)

P value

^*values are statistically significant at P < 0.05.

Age (years)

< 0.001*

Males (n, %)

34 (0.34)

32 (0.64)

< 0.001*

Females (n, %)

66 (0.66)

18 (0.36)

< 0.001*

Hypertension (n, %)

45 (0.45)

28 (0.54)

0.204

Diabetes (n, %)

42 (0.42)

10 (0.20)

0.007*

LVEF (%)

0.189

LVIDd (cm)

4.4

4.3

0.182

LVIDs (cm)

2.9

2.7

0.095

Septal thickness (cm)

1.25

1.14

0.003*

Post wall thickness (cm)

1.19

1.09

0.003*

LA dimension (cm)

4.1

3.4

< 0.001*

Peak mitral E (cm/s)

< 0.001*

E/a

1.5

1.0

< 0.001*

e’ (cm/s)

8.0

9.0

0.069

E/e’

12.9

8.3

< 0.001*

Sa (cm/s)

7.5

9.7

< 0.001*

Systolic strain (%)

-12.3

-15.4

< 0.001*

Systolic strain rate (s^-1)

-1.07

0.957

**Table 3.** Baseline Demographics and Echocardiographic Parameters for All-cause Readmission
variable	Not Readmitted (n=35)	Readmitted, all-cause (n=65)	P value
^*values are statistically significant at P < 0.05.
Age (years)	76	77	0.666
Index Length of stay (days)	5.09	5.14	0.940
Males (n, %)	8 (0.23)	26 (0.40)	0.121
Females (n, %)	27 (0.77)	39 (0.60)	0.121
Hypertension (n, %)	16 (0.46)	29 (0.45)	0.916
Diabetes (n, %)	8 (0.24)	34 (0.52)	0.004*
BNP (pg/mL)	912	925	0.788
LVEF (%)	67	65	0.069
LVIDd (cm)	4.3	4.5	0.108
LVIDs (cm)	2.8	3	0.104
Septal thickness (cm)	1.2	1.3	0.361
Post wall thickness (cm)	1.2	1.2	0.328
LA dimension (cm)	4.2	4.1	0.858
Peak mitral E (cm/s)	94	96	0.755
E/a	1.7	1.4	0.240
E’ (cm/s)	8.3	7.9	0.726
E/e’	11.2	13.8	0.104
Sa (cm/s)	7.6	7.5	0.840
Systolic strain (%)	-12.72	-12.08	0.532
Systolic strain rate (s^-1)	-1.11	-1.05	0.447

Table 3. Baseline Demographics and Echocardiographic Parameters for All-cause Readmission

variable

Not Readmitted (n=35)

Readmitted, all-cause (n=65)

P value

^*values are statistically significant at P < 0.05.

Age (years)

0.666

Index Length of stay (days)

5.09

5.14

0.940

Males (n, %)

8 (0.23)

26 (0.40)

0.121

Females (n, %)

27 (0.77)

39 (0.60)

0.121

Hypertension (n, %)

16 (0.46)

29 (0.45)

0.916

Diabetes (n, %)

8 (0.24)

34 (0.52)

0.004*

BNP (pg/mL)

912

925

0.788

LVEF (%)

0.069

LVIDd (cm)

4.3

4.5

0.108

LVIDs (cm)

2.8

0.104

Septal thickness (cm)

1.2

1.3

0.361

Post wall thickness (cm)

1.2

0.328

LA dimension (cm)

4.2

4.1

0.858

Peak mitral E (cm/s)

0.755

E/a

1.7

1.4

0.240

E’ (cm/s)

8.3

7.9

0.726

E/e’

11.2

13.8

0.104

Sa (cm/s)

7.6

7.5

0.840

Systolic strain (%)

-12.72

-12.08

0.532

Systolic strain rate (s^-1)

-1.11

-1.05

0.447