Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access
Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc
Journal website http://www.cardiologyres.org

Original Article

Volume 11, Number 5, October 2020, pages 311-318


Low-Density Lipoprotein Cholesterol Targets in Patients With Coronary Heart Disease in Extremadura (Spain): LYNX Registry

Figure

Figure 1.
Figure 1. Distribution of use of the different statins.

Tables

Table 1. General Characteristics of the Study Population (N = 674)
 
Clinical variablesResults
CHD: coronary heart disease; CVD: cardiovascular disease.
Age (years)65.6 ± 12.1
Age of onset of CHD (years)59.4 ± 12.0
Women (%)19.3
Weight (kg)78.1 ± 14.7
Size (cm)165.0 ± 9.4
Body mass index (BMI) (kg/m2)28.6 ± 4.3
Nutritional condition
  Low weight (BMI < 18.4) (%)0.2
  Normal weight (BMI 18.5 - 24.9) (%)18.1
  Overweight (BMI 25 - 29.9) (%)48.1
  Obesity (BMI > 30) (%)33.6
Waist circumference (cm)101.7 ± 10.6
  > 102 in man (%)46
  > 88 in women (%)90.7
Active smoker (%)15.3
Arterial hypertension (%)63.6
Diabetes mellitus (%)38.7
Dyslipidemia (%)66.6
Family history of premature CVD (%)37.9
Peripheral artery disease (%)10.4
Cerebrovascular disease (%)7.1
Atrial fibrillation (%)12.6

 

Table 2. Analytical Values of the Whole Sample (Mean ± Standard Deviation)
 
HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; HbA1c: glycosylated hemoglobin.
Total cholesterol (mg/dL)139.2 ± 31.1
LDL-C (mg/dL)68.3 ± 24.5
HDL-C (mg/dL)47.3 ± 13.9
Triglycerides (mg/dL)119.3 ± 69.3
Non-HDL cholesterol (mg/dL)91.9 ± 28.3
Creatinine (mg/dL)1.1 ± 0.7
Glucose (mg/dL)112.4 ± 34.6
HbA1c (%)6.1 ± 1.0

 

Table 3. Factors Independently Associated With LDL-C < 70 mg/dL (Logistic Regression)
 
OR (95% CI)P
Statistical C = 0.67 (0.63 - 0.71). Hosmer-Lemeshow calibration P = 0.23. OR: odds ratio; CI: confidence interval; LDL-C: low-density lipoprotein cholesterol.
Female sex1.7 (1.12 - 2.48)0.01
Diabetes0.7 (0.50 - 0.96)0.03
Active smoker2.0 (1.29 - 3.11)0.002
Multivessel CHD1.5 (1.03 - 2.16)0.03
High-intensity statins0.7 (0.46 - 0.92)0.01
Ezetimibe0.6 (0.45 - 0.91)0.01
Atrial fibrillation1.9 (1.14 - 3.02)0.01