Figure 1. Unadjusted HRs for primary outcome (all events) associated with advanced atherosclerosis on carotid artery (type III-IV b finding) as a function of statin use. HR: hazard ratio. P < 0.0001
| Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access |
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Original Article
Volume 12, Number 6, December 2021, pages 335-339
Effect of Statin Treatment in Patients With Advanced Carotid Atherosclerosis: An Observational Outcome Study
Figure
Table
| Characteristics | Type III, IV b (n = 260) with statin therapy | Type III, IV b (n = 339) without statin therapy | P value |
|---|---|---|---|
| BMI: body mass index; LDL: low-density lipoprotein; HDL: high-density lipoprotein; PROCAM: Prospective Cardiovascular Munster Study for Fatal and Non-Fatal Myocardial Infarction; SD: standard deviation. | |||
| Age (years), mean ± SD | 55 ± 6 | 54 ± 6 | 0.0384 |
| BMI (kg/m2), mean ± SD | 27.58 ± 4.71 | 27.15 ± 4.00 | 0.4731 |
| Smoker, n (%) | 100 (38.5%) | 146 (43.1%) | 0.256 |
| LDL-cholesterol, mean ± SD | 162 ± 48 | 157 ± 34 | 0.4562 |
| HDL-cholesterol, mean ± SD | 52 ± 13 | 51 ± 13 | 0.2445 |
| Triglyceride, mean ± SD | 176 ± 113 | 176 ± 107 | 0.8166 |
| Systolic blood pressure (mm Hg), mean ± SD | 133 ± 18 | 133 ± 19 | 0.9807 |
| Diastolic blood pressure (mm Hg), mean ± SD | 82 ± 9 | 83 ± 11 | 0.1644 |
| Diabetes, n (%) | 29 (11.1%) | 21 (6.2%) | 0.0296 |
| Treated blood pressure (mm Hg), n (%) | 122 (46.9%) | 108 (31.9%) | 0.0002 |
| Positive family history, n (%) | 87 (33.5%) | 101 (29.8%) | 0.3786 |
| Total plaque area (mm2), mean ± SD | 143 ± 63 | 140 ± 61 | 0.407 |
| Maximum plaque thickness (mm), mean ± SD | 3.1 ± 0.8 | 3.0 ± 0.7 | 0.2853 |
| PROCAM risk, mean ± SD | 12.14±11.33% | 11.45±9.10% | 0.7425 |
| Event (infarction, stroke, etc.), n (%) | 14 (5.4%) | 80 (23.9%) | < 0.0001 |
| Cardiovascular death, n (%) | 1 (0.4%) | 11 (3.5%) | 0.0158 |
| Follow-up time (months) (min. - max.) | 46 (0 - 130) | 43 (0 - 124) | 0.5305 |