Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access
Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc
Journal website https://www.cardiologyres.org

Original Article

Volume 15, Number 3, June 2024, pages 129-133


Disparity in the Under-Utilization of Novel P2Y12 Inhibitors in ST-Elevation Myocardial Infarction Following Percutaneous Coronary Intervention

Figure

Figure 1.
Figure 1. Odds ratio of being discharged on clopidogrel following STEMI. Numbers represented next to the group are odds ratio (confidence interval). STEMI: ST-elevation myocardial infarction; CI: confidence interval.

Tables

Table 1. Baseline Characteristics of Patients Presenting With STEMI (From January 1, 2018 to December 31, 2021 in Our Cohort)
 
BaselineClopidogrel (n = 188)Ticagrelor (n = 125)Prasugrel (n = 53)
Quantitative values have measure of central tendency and dispersion in parenthesis, and qualitative values have number and percentage of the total in parenthesis. STEMI: ST-elevation myocardial infarction; AA: African Americans; BMI: body mass index; TIA: transient ischemic attack; ESRD: end-stage renal disease; HD: hemodialysis; PVD: peripheral vascular disease.
Age (mean)65 (± 12.5)60 (± 12.0)54 (± 9.9)
Age ≥ 7549 (26.1%)13 (10.4%)0 (0%)
Female sex65 (34.6%)34 (27.2%)11 (20.8%)
Male sex123 (65.4%)91 (72.8%)42 (79.2%)
Race
  White118 (62.8%)88 (70.4%)37 (69.8%)
  AA54 (28.7%)28 (22.4%)12 (22.6%)
  Asian6 (3.2%)4 (3.2%)2 (3.8%)
  Hispanic5 (2.7%)2 (1.6%)0 (0%)
Health insurance
  Medicare72 (38.3%)35 (28.0%)4 (7.5%)
  Medicaid19 (10.1%)9 (7.2%)5 (9.4%)
  Private142 (75.5%)99 (79.2%)47 (88.7%)
  No insurance5 (2.7%)1 (0.8%)0 (0%)
BMI30 (± 6.3)28 (± 5.4)29 (± 5.2)
Weight < 60 kg11 (5.9%)6 (4.8%)1 (1.9%)
Current/recent smoker59 (31.4%)34 (27.2%)18 (34.0%)
Hypertension133 (70.7%)89 (71.2%)27 (50.9%)
Diabetes53 (28.2%)39 (31.2%)13 (24.5%)
ESRD on HD1 (0.5%)1 (0.8%)1 (1.9%)
Dyslipidemia108 (57.4%)74 (59.2%)23 (43.4%)
Stroke/TIA19 (10.1%)12 (9.6%)0 (0%)
PVD7 (3.7%)7 (5.6%)0 (0%)
Chronic lung disease16 (8.5%)11 (8.8%)3 (5.7%)
Apixaban21 (11.2%)3 (2.4%)2 (3.8%)
Rivaroxaban5 (2.7%)1 (0.8%)0 (0%)
Dabigatran0 (0%)0 (0%)0 (0%)
Warfarin4 (2.1%)0 (0%)0 (0%)

 

Table 2. Percentage of Patients Being Prescribed Clopidogrel and Ticagrelor or Prasugrel at Discharge Following Admission for STEMI
 
ClopidogrelTicagrelor or prasugrelCI, P value
STEMI: ST-elevation myocardial infarction; CI: confidence interval.
Race
  White48.6%51.4%0.91 - 2.25, 0.115
  Non-White57.5%42.5%
Sex
  Male48.0%52.0%0.99 - 2.46, 0.053
  Female59.1%40.9%
Insurance
  Private insurance49.3%50.7%1.22 - 2.74, 0.003
  Non-private insurance64.0%36.0%