Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access
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Review

Volume 15, Number 5, October 2024, pages 330-339

The Role of Inducible Nitric Oxide Synthase in Assessing the Functional Level of Coronary Artery Lesions in Chronic Coronary Syndrome

Figures

Figure 1.
Figure 1. Representation of the role of iNOS in assessing the functional level of coronary artery lesions. MPO: myeloperoxidase; NO: nitric oxide; iNOS: inducible nitric oxide synthase; eNOS: endothelial nitric oxide synthase; ROS: reactive oxygen species; HOCl: hypochlorous acid; H2O2: hydrogen peroxide; NADPH: nicotinamide adenine dinucleotide phosphate; GC: guanylate cyclase; cGMP: cyclic guanosine monophosphate; FFR: fractional flow reserve; NHPR: nonhyperemic pressure ratio.
Figure 2.
Figure 2. Schematic representation of the control of vascular tone mediated by the MPO-H2O2 reaction pathway. MPO: myeloperoxidase; NO: nitric oxide; iNOS: inducible nitric oxide synthase; HOCl: hypochlorous acid; H2O2: hydrogen peroxide; H4B: tetrahydrobiopterin; VSMC: vascular smooth muscle cell; NADPH: nicotinamide adenine dinucleotide phosphate; L-Arg: L-arginine; EC: endothelial cell.