| Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc |
| Journal website https://www.cardiologyres.org |
Original Article
Volume 3, Number 5, October 2012, pages 209-213
Clopidogrel Within Few Hours of Coronary Artery Bypass Grafting Does Significantly Increase the Risk of Bleeding
Tables
| Clopidogrel group (65 cases) | No Clopedogril group (206 cases) | P value | |
|---|---|---|---|
| TIA: Transient ischemic attacks; C.R.F: Chronic renal failure; P.V.D: Peripheral vascular disease; COPD: Chronic obstructive pulmonary disease; BMI: Body mass index. | |||
| The average age | 64.9 years (range, 39 to 83 years) | 63.2 years (range, 36 to 80 years) | |
| Male | 40 | 146 | 0.157 |
| Female | 25 | 60 | |
| Age | 57.3 | 61 | 0.440 |
| Diabetes | 26 | 100 | 0.228 |
| C.R.F | 1 | 2 | 0.562 |
| P.V.D | 5 | 15 | 0.548 |
| COPD | 12 | 29 | 0.389 |
| Smoking | 42 | 152 | 0.152 |
| Heamoglubin | 11.9 | 12.3 | 0.155 |
| X Clamp time (minutes) | 39 | 36 | 0.126 |
| Bypass time (minutes) | 76 | 83 | 0.190 |
| No of grafts | 2.7 | 3.1 | 0.359 |
| Steroid use | 3 | 5 | 0.294 |
| Obesity (BMI > 25 kg/m2) | 8 | 11 | 0.056 |
| Group | Total | ||
|---|---|---|---|
| Clopedogril Group | No Clopedogril Group | ||
| *Cryo. Transfusion, Blood Transfusion, FFP Transfusion, Platelets Transfusion, Platelets Transfusion = (Units) | |||
| Blood Transfusion | < 0.001 | ||
| 1 - 2 | 0 (0.0) | 186 (90.3) | |
| 3 | 20 (30.8) | 20 (9.7) | |
| 4 - 5 | 45 (69.2) | 0 (0.0) | |
| FFP Transfusion | < 0.001 | ||
| 4 - 6 | 16 (24.6) | 206 (100.0) | |
| 8 - 10 | 49 (75.4) | 0 (0.0) | |
| Cryo Transfusion | < 0.001 | ||
| 0 | 0 (0.0) | 206 (100.0) | |
| 6 - 8 | 65 (100.0) | 0 (0.0) | |
| Platelets Transfusion | < 0.001 | ||
| 4.00 | 0 (0.0) | 170 (82.5) | |
| 6.00 | 25 (38.5) | 36 (17.5) | |
| 10.00 | 40 (61.5) | 0 (0.0) | |
| Mediastinal drainage, mean (SD), median (mL) | 1230.6 (118.5);1210.0 | 791.3 (117.4); 785.0 | < 0.001 |
| ITU stay (days) | 3.3 | 3.1 | 0.151 |
| Total Hospital stay (days) | 7.1 | 7.14 | 0.187 |
| Re-exploration-Number of patients | 9 (13.8%) | 6 (2.9%) | 0.001 |