Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access
Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc
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Case Report

Volume 4, Number 2, April 2013, pages 78-81


A Case of Fulminant Myocarditis With Preceding Repeated Episodes of Congestive Heart Failure

Figures

Figure 1.
Figure 1. Electrocardiography. In January 2010, premature ventricular contractions and left anterior hemiblock were seen (Left). On admission in March 2010, conduction disturbance was suggested from wide QRS and Q wave in multiple leads appeared (Right).
Figure 2.
Figure 2. Hematoxylin- Eosin staining. Endomyocardial biopsy was performed from right ventricular septum on the 4th hospital day. The biopsied specimen was formalin fixed and paraffin embedded, (square: high power field).
Figure 3.
Figure 3. Azan staining. Azan staining showed extensive fibrosis.
Figure 4.
Figure 4. Immunohistochemical staining. Immunohistochemical staining of 5-µm-thick thin sections was performed with primary antibodies for identifying each cell; T lymphocytes: anti-CD3 antibody (Dako, Glostrup, Denmark), B lymphocytes and Plasma cells: anti-CD20 and anti-CD79a antibodies (Dako), monocytes and macrophages: anti-CD68 (Dako). Incubation with an avidin-biotin-blocking system and secondary antibody and peroxidase-labeled avidin-biotin complex system (Dako) was performed then. Localization of the primary antibody was visualized with 3, 3’ diaminobenzidine (DAB), followed by counterstaining with hematoxylin. Upper left: CD68, lower left: CD20, lower right: CD79a, upper right: CD3