Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access
Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc
Journal website https://www.cardiologyres.org

Original Article

Volume 5, Number 1, February 2014, pages 12-22

Atrial Fibrillation and Cardiovascular Comorbidities, Survival and Mortality: A Real-Life Observational Study

Figures

Figure 1.
Figure 1. Longitudinal relationship between cardiovascular complications and atrial fibrillation. *Vascular complication.
Figure 2.
Figure 2. Survival curve in patients with > 2 diagnosed CVC.
Figure 3.
Figure 3. Survival curve and treatment with oral anticoagulant agents.
Figure 4.
Figure 4. Survival curve in AF patients without CVC.
Figure 5.
Figure 5. Survival curve to 5 years after AF diagnosis.

Tables

Table 1. Subjects Characteristics and Cardiovascular Risk Factors Prevalence in AF Affected Patients
 
VariablesGeneral population without AFPopulation with AFP
N 1,043 269
Women (%) 52.9 49.8 0.398
Mean age (years) 72.44 ± 7.59 78.7 ± 7.30 < 0.001
Type of population (%)
  Rural 16.4 16.2 1
  Semi-urban 37.5 36.9 0.91
  Urban 46.1 46.9 0.88
Age groups (%)
  < 65 15.7 3.7 < 0.001
  65-74 40.9 21.4 < 0.001
  ≥ 75 43.3 74.9 < 0.001
Hypertension (%) 66 70.8 0.1468
Diabetes mellitus (%) 27 26.6 0.938
CHA2DS2-VASc score (%)
  0
  1 2.3 0 .7 0.16
  2 10.7 5.2 0.008
  3 24.2 13.3 < 0.001
  4 28.9 19.6 0.008
  5 21.4 28.0 0.025
  6 8.3 15.9 < 0.001
  7 2.2 12.2 < 0.001
  8 1.5 3.3 0.096
CHA2DS2-VASc ≥ 2 (%) 85.9 95.6 0.004

 

Table 2. Percentage of Specific Treatments
 
Overall group (%)CHA2DS2-VASc ≥ 2 (%)Lone FA (%)
Rate control treatment 54.6 38.7 51.08
Antiarrhythmic treatment 33.0 19.7 36.7
Oral anticoagulant treatment 77.7 53.3 78.2
Antiplatelet therapy 19.7 18.2 21.7
ACE-inhibitors treatment 60.9 46.2 56.5
Statins treatment 49.0 35.5 38.0

 

Table 3. Accumulated Mortality by Gender and Period From AF Diagnosis
 
NMortality
1 year		Mortality
5 years		Mortality
10 years		Total
Women 130 - 12/14
85.7% (95% IC)		 2/14
14.2% (95% IC)		 14 (10.7%)
Men 135 1/17
(5.8%)		 5/17
29.4% (95% IC)		 12/17
70.5% (95% IC)		 17 (12.6%)
Total 265 17/31 (54.8%) 21/23 31 (11.7%)
P value 0.157 0.380 0.562