Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access |
Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc |
Journal website https://www.cardiologyres.org |
Original Article
Volume 2, Number 2, April 2011, pages 66-71
Upper Digestive Bleeding in Atrial Fibrillation: Evaluation of Gastroscopy Prior to Oral Anticoagulant Therapy (GOAT), Prospective, Randomized, Double Blind Study on a Community Population
Figure
Table
Group A | Group B | P | |
---|---|---|---|
*NS = not significant | |||
Patient number | 114 | 101 | |
Age (mean (range)) | 74 (45 - 86) | 77 (42 - 84) | NS* |
Males | 68 | 71 | NS |
INR > 4.5 | 26 | 20 | NS |
NSAIDS or Aspirin or corticosteroids | 14 | 11 | NS |
Platelet antiaggregants | 14 | 7 | NS |
Antihypertensive drugs | 41 | 50 | NS |
Diabetes | 7 | 7 | NS |
History of cancer | 2 | 1 | |
Previous digestive diseases or symptoms | 6 | 7 | NS |
Alcohol or smoking | 14 | 16 | NS |
Co-morbidities (Renal, COPD, Heart failure, or Coronaropathy) | 51 | 45 | NS |
β-blockers | 79 | 81 | NS |
Propafenone/flecainide | 30 | 45 | < 0.001 |
Amiodarone | 41 | 51 | < 0.05 |
Early hemorrhages | 2 (1.7%) | 12 (12%) | < 0.001 |
Late hemorrhages | 4 (3.5%) | 6 (6%) | NS |
Lost at follow up | 10 | 12 | NS |