Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access
Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc
Journal website https://www.cardiologyres.org

Original Article

Volume 7, Number 4, August 2016, pages 140-145

Fragmented QRS as a Marker of Electrical Dyssynchrony to Predict Inter-Ventricular Conduction Defect by Subsequent Echocardiographic Assessment in Symptomatic Patients of Non-Ischemic Dilated Cardiomyopathy

Figures

Figure 1.
Figure 1. Different types of fragmented QRS (fQRS).
Figure 2.
Figure 2. Tissue Doppler imaging to calculate “Yu index”.
Figure 3.
Figure 3. Sensitivity, specificity, positive predictive value and negative predictive value of fQRS complexes to detect intraventricular dyssynchrony.
Figure 4.
Figure 4. Segmental distribution of fQRS (n = 114).

Table

Table 1. Baseline Clinical, Electrocardiographic and Echocardiographic Parameters of Patients (n = 226)
 
VariablesfQRS (n = 112; %)nQRS (n = 114; %)P value
NYHA: New York Heart Association; ACE-I: angiotensin converting enzyme inhibitor; ARB: angiotensin receptor blocker; LVEF: left ventricular ejection fraction; LVEDD: left ventricular end-diastolic dimension; LVESD: left ventricular end-systolic dimension; fQRS: fragmented QRS; nQRS: normal QRS.
Age (years)45.88 ± 13.7047.84 ± 14.070.48
Sex (M/F)81 (73):31 (27)79 (69):35 (31)0.56
NYHA class (II/III/IV)59 (52)/40 (35)/13 (11)63 (55)/43 (38)/8 (7)0.22
Medications use
  Beta blocker96 (86)102 (89.5)0.53
  Diuretic105 (94)110 (96.5)0.53
  ACE-I/ ARB85 (76)93 (81.5)0.66
  Digoxin43(38.4)49 (43)0.66
QRS duration (ms)102.42 ± 14.0591.10 ± 13.750.001
LVEF (%)28.24 ± 5.0827.245 ± 9.20.07
LVEDD (mm)62.42 ± 8.1060.6 ± 8.010.28
LVESD (mm)54.1 ± 8.551.8 ± 7.320.13
Ts-SD (Yu index)35.64 ± 12.7920.45 ± 11.170.01
Yu index positive patient88 (78.6)24 (21.1)0.04