Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access |
Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc |
Journal website https://www.cardiologyres.org |
Original Article
Volume 8, Number 5, October 2017, pages 190-198
Occurrence and Impact of Time Delay to Primary Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction
Figures
Tables
Basic clinical and demographic variables in STEMI patients | All patients (n = 357) | Time from symptoms onset to hospital arrival | P value | Time from hospital arrival to cathlab arrival | P value | Door to first balloon time | P value | Time from cathlab arrival to first balloon | P value | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Within 3 h (57.4%) | After 3 h (42.6%) | Within 30 min (59.4%) | After 30 min (40.6%) | Within 90 min (63.3%) | After 90 min (36.7%) | Within 1 h (78.4%) | After 1 h (21.6%) | ||||||
Mean age in years | 62.3 | 62.2 | 62.8 | 0.65 | 62.1 | 63.3 | 0.66 | 61.8 | 63 | 0.4 | 62.1 | 62.8 | 0.68 |
Male sex | 80.7 | 50.3 | 30.4 | 0.22 | 58.7 | 22 | 0.4 | 50.4 | 30.3 | 0.3 | 63.1 | 17.6 | 0.45 |
Female sex | 19.3 | 9.2 | 10.1 | 0.4 | 13.3 | 6 | 0.2 | 12.9 | 6.4 | 0.3 | 15.4 | 3.9 | 0.3 |
Positive family history of CAD | 21.6 | 15.4 | 6.2 | 0.07 | 15.8 | 5.8 | 0.45 | 14 | 7.6 | 0.4 | 17.4 | 4.2 | 0.37 |
DM | 15.1 | 7.5 | 7.6 | 0.34 | 13.1 | 2 | 0.6 | 10.1 | 5 | 0.34 | 12.6 | 2.5 | 0.22 |
HTN | 54.3 | 33.1 | 21.2 | 0.5 | 35.9 | 18.4 | 0.28 | 34.1 | 20.2 | 0.47 | 42 | 12.3 | 0.33 |
Hypercholesterolemia | 66.4 | 41 | 25.4 | 0.17 | 46.3 | 20.1 | 0.23 | 41.5 | 24.9 | 0.36 | 52.4 | 14 | 0.43 |
Previous MI | 8.1 | 6.5 | 1.6 | 0.029 | 6.1 | 2 | 0.065 | 5.3 | 2.8 | 0.48 | 6.1 | 2 | 0.43 |
Previous PCI | 9 | 8.1 | 0.9 | 0.02 | 6.4 | 2.6 | 0.7 | 5.3 | 3.7 | 0.47 | 6.2 | 2.8 | 0.18 |
Previous CABG | 2.5 | 1.6 | 0.9 | 0.61 | 2 | 0.5 | 0.64 | 2 | 0.5 | 0.29 | 1.7 | 0.8 | 0.3 |
CHF | 0.6 | 0.5 | 0.1 | 0.61 | 0.3 | 0.3 | 0.25 | 0.3 | 0.3 | 0.26 | 0.6 | 0 | 0.6 |
Previous stroke | 2.2 | 0.8 | 1.4 | 0.013 | 1.1 | 1.1 | 0.62 | 1.4 | 0.8 | 0.61 | 2 | 0.2 | 0.68 |
Current smokers | 43.4 | 30.7 | 12.7 | 0.56 | 30.4 | 13 | 0.48 | 27.7 | 15.7 | 0.97 | 32.6 | 11.8 | 0.075 |
Peak CK-MB | 60 | 47 | 103 | 0.000 | 58 | 80 | 0.063 | 56 | 68 | 0.74 | 57 | 76 | 0.21 |
Peak troponin T | 0.51 | 0.36 | 1 | 0.000 | 0.51 | 0.54 | 0.075 | 0.36 | 0.77 | 0.0006 | 0.38 | 1 | 0.005 |
Outcome variables at 0 day, 30 days and 1 year for STEMI patients | All patients (n = 357) | Time from symptoms onset to hospital arrival | P value | Time from hospital arrival to cathlab arrival | P value | Door to balloon time | P value | Time from cathlab arrival to first balloon | P value | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Within 3 h (57.4%) | After 3 h (42.6%) | Within 30 min (59.4%) | After 30 min (40.6%) | Within 90 min (63.3%) | After 90 min (36.7%) | Within 1 h (78.4%) | After 1 h (21.6%) | ||||||
All deaths at 0 day | 1.7 | 1.1 | 0.6 | 0.66 | 1.4 | 0.3 | 0.44 | 0.8 | 0.9 | 0.49 | 0.8 | 0.9 | 0.088 |
Cardiac deaths at 0 day | 1.4 | 0.9 | 0.5 | 0.75 | 1.2 | 0.2 | 0.48 | 0.6 | 0.8 | 0.27 | 0.6 | 0.8 | 0.035 |
Any MI at 0 day (in hospital reinfarction) | 0.6 | 0.3 | 0.3 | 0.34 | 0.5 | 0.1 | 0.73 | 0.3 | 0.3 | 0.69 | 0 | 0.6 | 0.007 |
Recurrent revascularization at 0 day | 0.8 | 0.5 | 0.3 | 0.5 | 0.6 | 0.2 | 0.63 | 0.2 | 0.6 | 0.28 | 0.2 | 0.6 | 0.056 |
Stent thrombosis at 0 day | 0.3 | 0 | 0.3 | 0.21 | 0.2 | 0.1 | 0.86 | 0.3 | 0 | 0.44 | 0 | 0.3 | 0.056 |
Cerebrovascular events at 0 day | 0 | 0 | 0 | - | 0 | 0 | - | 0 | 0 | - | 0 | 0 | - |
MAACE at 0 day | 2.2 | 1.3 | 0.9 | 0.5 | 1.5 | 0.7 | 0.5 | 0.8 | 1.4 | 0.12 | 0.8 | 1.4 | 0.004 |
Bleeding at 0 day | 5.6 | 3.2 | 2.4 | 0.45 | 3.6 | 2 | 0.4 | 3.9 | 1.7 | 0.52 | 4.5 | 1.1 | 0.86 |
All deaths at 30 days | 1.7 | 1.1 | 0.6 | 0.63 | 1.5 | 0.2 | 0.45 | 0.8 | 0.9 | 0.49 | 0.8 | 0.9 | 0.088 |
Cardiac deaths at 30 days | 1.4 | 0.9 | 0.5 | 0.7 | 1.2 | 0.2 | 0.46 | 0.6 | 0.8 | 0.27 | 0.6 | 0.8 | 0.035 |
Any MI at 30 days | 0.8 | 0.5 | 0.3 | 0.5 | 0.7 | 0.1 | 63 | 0 | 0.8 | 0.9 | 0 | 0.8 | 0.001 |
Recurrent revascularization at 30 days | 2 | 1.3 | 0.7 | 0.54 | 1.7 | 0.3 | 0.67 | 1.1 | 0.9 | 0.73 | 1.1 | 0.9 | 0.16 |
Stent thrombosis at 30 days | 0.8 | 0.5 | 0.3 | 0.51 | 0.8 | 0 | 0.63 | 0.8 | 0 | 0.18 | 0.3 | 0.5 | 0.056 |
Cerebrovascular events at 30 days | 0 | 0 | 0 | - | 0 | 0 | - | 0 | 0 | - | 0 | 0 | - |
MAACE at 30 days | 3.6 | 2.2 | 1.4 | 0.55 | 1.8 | 1.8 | 0.32 | 2 | 1.6 | 0.46 | 2 | 1.6 | 0.069 |
Bleeding at 30 days | 6.4 | 3.8 | 2.6 | 0.38 | 4.6 | 1.8 | 0.62 | 4.4 | 2 | 0.52 | 5.3 | 1.1 | 0.61 |
All deaths at 1 year | 3.6 | 2.2 | 1.4 | 0.3 | 3 | 0.6 | 0.13 | 2.5 | 1.1 | 0.65 | 2.8 | 0.8 | 0.89 |
Cardiac deaths at 1 year | 2.2 | 1.2 | 1 | 0.54 | 2 | 0.2 | 0.3 | 1.4 | 0.8 | 0.96 | 1.4 | 0.8 | 0.26 |
Any MI at 1 year | 2.5 | 0.9 | 1.6 | 0.008 | 2.1 | 0.4 | 0.25 | 2 | 5 | 0.36 | 1.1 | 1.4 | 0.012 |
Recurrent revascularization at 1 year | 5.3 | 3 | 2.3 | 0.2 | 4.3 | 1 | 0.49 | 4.2 | 1.1 | 0.14 | 3.6 | 1.6 | 0.27 |
Stent thrombosis at 1 year | 1.4 | 0.8 | 0.6 | 0.28 | 1 | 0.4 | 0.46 | 1.4 | 0 | 0.32 | 0.6 | 0.8 | 0.056 |
Cerebrovascular events at 1 year | 0.3 | 0 | 0.3 | 0.2 | 0.3 | 0 | 0.86 | 0.3 | 0 | 0.69 | 0.3 | 0 | 0.69 |
MAACE at 1 year | 7.8 | 4.9 | 2.9 | 0.12 | 4.6 | 3.2 | 0.2 | 5.6 | 2.2 | 0.35 | 5 | 2.8 | 0.057 |
Bleeding at 1 year | 9.2 | 5.7 | 3.5 | 0.25 | 6.8 | 2.4 | 0.5 | 6.2 | 3.1 | 0.67 | 7.6 | 1.7 | 0.62 |