| Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc |
| Journal website https://www.cardiologyres.org |
Original Article
Volume 9, Number 1, February 2018, pages 7-10
Effects of Preoperative Curcumin on the Inflammatory Response During Mechanical Circulatory Support: A Porcine Model
Table
| Inflammatory marker | Curcumin (seven samples) Median (IQR) | Control (16 samples) Median (IQR) | Difference in medians (95% CI) | P value |
|---|---|---|---|---|
| *Concentrations below limits of detection rendered as 0. Sample concentrations are compared using non-parametric methods to account for unquantifiable low concentrations in some samples. CI: confidence interval; ICAM: intercellular adhesion molecule; IL: interleukin; IQR: interquartile range; TNF: tumor necrosis factor. | ||||
| IL-1b | 0 (0, 0)* | 0 (0, 52) | 0 (0, 0) | 0.105 |
| IL-6 | 251 (201, 315) | 324 (177, 815) | 73 (-68, 482) | 0.349 |
| IL-8 | 0 (0, 0) | 0 (0, 11) | 0 (0, 0) | 0.517 |
| TNF-α | 303 (144, 387) | 413 (307, 697) | 110 (20, 388) | 0.045 |
| ICAM-1 | 23 (20, 31) | 40 (29, 45) | 17 (7, 22) | 0.019 |