Cardiol Res

Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access

Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc

Journal website https://www.cardiologyres.org

Original Article

Volume 2, Number 1, February 2011, pages 36-41

Application of Mitral Annular Systolic Displacements and Velocities for the Evaluation of Left Ventricular Systolic Function and Reserve

Figure 1. Relation between left ventricular WMSI and mitral annular translation distance at rest (a) and after dobutamine stress (b); and between mitral annular systolic velocities at rest (c) and after dobutamine stress (d).

**Table 1.** Longitudinal Mitral Annular Translation (mm)
	Septal	Lateral	Inferior	Anterior	Posterior
WMA: Wall motion abnormality
* P-value Pre and Post DSE
‡P-value with and without WMA
WMA	At rest	10.5 ± 4	13.4 ± 3	12.2 ± 0.5	12.7 ± 2.6	12.3 ± 2.4
	Post-DSE	11.7 ± 3.8	14 ± 1.75	12.3 ± 1.89	11.9 ± 2.5	13 ± 0.8
	P-value*	n.s.	n.s.	n.s.	n.s.	n.s.
No WMA	At rest	13.2 ± 2	15.6 ± 2.6	15 ± 3	15.2 ± 2.6	14.5 ± 2.9
	Post-DSE	14 ± 2.25	16.4 ± 2.6	15.75 ± 2.8	15.6 ± 2.8	15.7 ± 2.3
	P-value*	n.s.	n.s.	n.s.	n.s.	n.s.
P-value‡	At rest	0.015	0.096	0.002	0.02	0.03
	Post-DSE	0.036	0.067	0.001	0.042	0.006

Table 1. Longitudinal Mitral Annular Translation (mm)

Septal

Lateral

Inferior

Posterior

WMA: Wall motion abnormality

* P-value Pre and Post DSE

‡P-value with and without WMA

WMA

At rest

10.5 ± 4

13.4 ± 3

12.2 ± 0.5

12.7 ± 2.6

12.3 ± 2.4

Post-DSE

11.7 ± 3.8

14 ± 1.75

12.3 ± 1.89

11.9 ± 2.5

13 ± 0.8

P-value*

n.s.

No WMA

At rest

13.2 ± 2

15.6 ± 2.6

15 ± 3

15.2 ± 2.6

14.5 ± 2.9

Post-DSE

14 ± 2.25

16.4 ± 2.6

15.75 ± 2.8

15.6 ± 2.8

15.7 ± 2.3

P-value*

n.s.

P-value‡

At rest

0.015

0.096

0.002

0.02

0.03

Post-DSE

0.036

0.067

0.001

0.042

0.006

**Table 2.** Mitral Annular Translation and Velocities at Rest and After DSE in Different Wall Motion Subgroups
	Septal	Lateral
N: Normal wall motion at rest and after DSE
I: Ischemic - normal wall motion at rest and abnormal after DSE
A: Abnormal wall motion at rest and after DSE
Translation (mm)	N	13.2 ± 1.87	14.03 ± 1.98	0.167	15.6 ± 2.64	16.4 ± 2.37	0.292
	I	13.1 ± 2.3	14.1 ± 2.5	0.28	15.4 ± 1.83	17.4 ± 3.8	0.085
	A	10.45 ± 3.04	11.66 ± 3.7	0.34	13.3 ± 3.9	13.6 ± 3.86	0.89
p - (A : N)	0.0147	0.071		0.096	0.07
p - (A : I)	0.925	0.08		0.119	0.03
p - (N : I)	0.885	0.94		0.81	0.365
Velocity (cm/sec)	N	11.25 ± 3	17.8 ± 3.3	2 × 10^-10	12.7 ± 3	17 ± 4.1	0.00012
	I	11.2 ± 4.1	18 ± 5.2	0.00035	11.1 ± 2.8	18.7 ± 5.7	0.00023
	A	9.65 ± 2.6	14.5 ± 4.9	0.025	9.6 ± 2.6	13.7 ± 4.4	0.012
p - (A : N)	0.08	0.0395		0.0049	0.037
p - (A : I)	0.23	0.078		0.156	0.018
p - (N : I)	0.92	0.91		0.126	0.319

Table 2. Mitral Annular Translation and Velocities at Rest and After DSE in Different Wall Motion Subgroups

Septal

Lateral

rest

DSE

rest

DSE

N: Normal wall motion at rest and after DSE

I: Ischemic - normal wall motion at rest and abnormal after DSE

A: Abnormal wall motion at rest and after DSE

Translation (mm)

13.2 ± 1.87

14.03 ± 1.98

0.167

15.6 ± 2.64

16.4 ± 2.37

0.292

13.1 ± 2.3

14.1 ± 2.5

0.28

15.4 ± 1.83

17.4 ± 3.8

0.085

10.45 ± 3.04

11.66 ± 3.7

0.34

13.3 ± 3.9

13.6 ± 3.86

0.89

p - (A : N)

0.0147

0.071

0.096

0.07

p - (A : I)

0.925

0.08

0.119

0.03

p - (N : I)

0.885

0.94

0.81

0.365

Velocity (cm/sec)

11.25 ± 3

17.8 ± 3.3

2 × 10^-10

12.7 ± 3

17 ± 4.1

0.00012

11.2 ± 4.1

18 ± 5.2

0.00035

11.1 ± 2.8

18.7 ± 5.7

0.00023

9.65 ± 2.6

14.5 ± 4.9

0.025

9.6 ± 2.6

13.7 ± 4.4

0.012

p - (A : N)

0.08

0.0395

0.0049

0.037

p - (A : I)

0.23

0.078

0.156

0.018

p - (N : I)

0.92

0.91

0.126

0.319

**Table 3.** Mitral Annular Peak Systolic Velocity (cm/sec)
	Septal	Lateral	Inferior	Anterior	Posterior
WMA: Wall motion abnormality
* P-value Pre and Post DSE
‡ P-value with and without WMA
WMA	At rest	9.7 ± 1.8	9.59 ± 2.6	9.2 ± 2.3	9.5 ± 1.4	9.3 ± 1.5
	Post-DSE	14.5 ± 4.5	13.7 ± 4.2	14.7 ± 5	18.7 ± 3.6	13.8 ± 4.8
	P-value*	0.025	4.3E-8	1.6E-8	4.5E-6	4.2E-12
No WMA	At rest	11.25 ± 2.7	12.7 ± 3.7	11.3 ± 1.8	11 ± 2.4	11.4 ± 2.4
	Post-DSE	17.8 ± 3.2	17 ± 3.7	16.9 ± 3.6	18.3 ±4.4	17.3 ± 4
	P-value*	1.99E-10	4.9E-8	1.9E-8	1.9E-5	6E-10
P-value‡	At rest	0.385	0.072	0.034	0.13	0.009
	Post-DSE	2.25E-6	0.05	0.038	0.23	0.05

Table 3. Mitral Annular Peak Systolic Velocity (cm/sec)

Septal

Lateral

Inferior

Posterior

WMA: Wall motion abnormality

* P-value Pre and Post DSE

‡ P-value with and without WMA

WMA

At rest

9.7 ± 1.8

9.59 ± 2.6

9.2 ± 2.3

9.5 ± 1.4

9.3 ± 1.5

Post-DSE

14.5 ± 4.5

13.7 ± 4.2

14.7 ± 5

18.7 ± 3.6

13.8 ± 4.8

P-value*

0.025

4.3E-8

1.6E-8

4.5E-6

4.2E-12

No WMA

At rest

11.25 ± 2.7

12.7 ± 3.7

11.3 ± 1.8

11 ± 2.4

11.4 ± 2.4

Post-DSE

17.8 ± 3.2

17 ± 3.7

16.9 ± 3.6

18.3 ±4.4

17.3 ± 4

P-value*

1.99E-10

4.9E-8

1.9E-8

1.9E-5

6E-10

P-value‡

At rest

0.385

0.072

0.034

0.13

0.009

Post-DSE

2.25E-6

0.05

0.038

0.23

0.05