Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access
Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc
Journal website https://www.cardiologyres.org

Original Article

Volume 2, Number 5, October 2011, pages 236-242

Bovine Intestinal Alkaline Phosphatase Reduces Inflammation After Induction of Acute Myocardial Infarction in Mice

Figures

Figure 1.
Figure 1. Production of the pro-inflammatory cytokine IL-6 after acute myocardial infarction. Mice were sacrificed at different time points and IL-6 production was determined (n = 3 per time point). Values are depicted as mean ± SEM.
Figure 2.
Figure 2. Alkaline phosphatase activity 4 hours after acute myocardial infarction. Values are depicted as mean ± SEM (n = 4 per treatment group). * P < 0.05 versus control
Figure 3.
Figure 3. Effect of bIAP on the production of the pro-inflammatory cytokines IL-6 and IL-1β and on the anti-inflammatory cytokine IL-10 4 hours after acute myocardial infarction. Levels of IL-6, IL-1β, and IL-10 were determined using specific ELISA; (■) control mice and (□) bIAP-treated mice. Values are depicted as mean ± SEM (n = 4 per treatment group). * P < 0.05 versus control.
Figure 4.
Figure 4. Effect of bIAP on the production of mMCP-1, 4 hours after acute myocardial infarction. Values are depicted as mean ± SEM (n = 4 per treatment group). * P < 0.05 versus control.