Cardiology Research, ISSN 1923-2829 print, 1923-2837 online, Open Access
Article copyright, the authors; Journal compilation copyright, Cardiol Res and Elmer Press Inc
Journal website http://www.cardiologyres.org

Original Article

Volume 10, Number 6, December 2019, pages 336-344


The Safety and Efficacy of Guidezilla Catheter (Mother-in-Child Catheter) in Complex Coronary Interventions: An Observational Study

Figures

Figure 1.
Figure 1. Indications for various uses of Guidezilla extension catheter in PCI. PCI: percutaneous coronary intervention.
Figure 2.
Figure 2. PCI of RCA having acute take-off origin (a); wired with Sion blue (Asahi, Japan) showing concertina effect (horizontal arrow; b, c). PCI: percutaneous coronary intervention; RCA: right coronary artery.
Figure 3.
Figure 3. Guidezilla catheter was extended up to mid-RCA (red arrowhead; a); 3.5 × 38 Endeavour Resolute (Zotarolimus-eluting stent, Medtronic, CA, USA) was positioned across the lesion after pulling Guidezilla into guiding catheter (red arrowhead; b); Lesion was stented after deploying stent at 14 atm pressure showing TIMI 3 flow (c). RCA: right coronary artery; atm: atmospheric pressure; TIMI: thrombolysis in myocardial infarction.
Figure 4.
Figure 4. Chronic total occlusion of RCA (a); It was wired with Fielder XT with caravel microcatheter support (Asahi, Japan) (b); GEC was pushed beyond the lesion with balloon anchoring technique (54 mm, red arrowhead; c); 3.5 × 42 Supralimus Grace (Sirolimus-eluting stent, Sajahanand Medical, Gujarat, India) was positioned across lesion after pulling Guidezilla into guiding catheter (red arrowhead; d); Lesion was stented after deploying stent at 14 atm pressure showing TIMI 3 flow (e). RCA: right coronary artery; GEC: Guidezilla extension catheter; atm: atmospheric pressure; TIMI: thrombolysis in myocardial infarction.
Figure 5.
Figure 5. Chronic total occlusion of ostial LAD which was wired with Conquest-Pro 12 with caravel microcatheter support. Lesion was predilated and GEC was pushed beyond the lesion (red arrowhead; a, b); 3.5 × 42 Supralimus Grace was positioned across the lesion (red arrow; b, c) after pulling Guidezilla into guiding catheter (red arrowhead; c, d); Lesion was stented at 14 atm pressure showing TIMI 3 flow by pulling it further and properly positioned across the lesion (d, e). LAD: left anterior descending; GEC: Guidezilla extension catheter; atm: atmospheric pressure; TIMI: thrombolysis in myocardial infarction.
Figure 6.
Figure 6. Tortuous diffuse lesion of LCX along with focal lesion of LAD (red arrow; a, b); LAD was stented with 3.5 × 18 mm Endeavour Resolute at 13 atm pressure achieving TIMI 3 flow (double arrow; c), and LCX was wired with Sion blue wire (c). LCX: left circumflex; LAD: left anterior descending; atm: atmospheric pressure; TIMI: thrombolysis in myocardial infarction.
Figure 7.
Figure 7. After adequate predilatation, GES was pushed beyond the lesion (73 mm, red arrow; a); 3.5 × 46 Supralimus Grace stent was positioned across the lesion after pulling Guidezilla into guiding catheter (red arrowhead; b); Lesion was stented after deploying stent at 14 atm pressure showing TIMI 3 flow (c). GEC: Guidezilla extension catheter; atm: atmospheric pressure; TIMI: thrombolysis in myocardial infarction.
Figure 8.
Figure 8. Critical stenosis of SVG to obtuse marginal branch of LCX at anastomotic site in a post-CABG patient who presented with stable angina of CCS class III (red arrowhead, a; red arrow, b). SVG: saphenous vein graft; LCX: left circumflex; CABG: coronary artery bypass graft; CCS: Canadian Cardiovascular Society.
Figure 9.
Figure 9. Lesion was wired using Sion blue wire and Guidezilla (red arrowhead) was advanced using buddy wire technique (a); Great difficulty was encountered to push GES which was further advanced with 2.5 × 10 mm sprinter legend balloon (red horizontal arrow, Medtronic, CA, USA) using BAT (b); 3 × 18 mm Endeavour Resolute stent (vertical arrow) was pushed beyond lesion by keeping buddy wire to garner adequate support (c). GEC: Guidezilla extension catheter; BAT: balloon-assisted tracking.
Figure 10.
Figure 10. Stent was pulled to position across the lesion after removing buddy wire and deployed at 13 atm pressure (arrowhead) (a); TIMI 3 flow was achieved along with concertina effect (multiple horizontal arrows) after withdrawing GEC (b); Smooth flow after removing the wire which removed concertina effect which was wire bias effect (c); Deep intubation of Guidezilla catheter (92 mm) (d). atm: atmospheric pressure; GEC: Guidezilla extension catheter; TIMI: thrombolysis in myocardial infarction.

Tables

Table 1. Baseline Characteristics of Patients (n = 156)
 
VariableN (%)
STEMI: ST-segment elevation myocardial infarction; NSTEMI: non-ST-segment elevation myocardial infarction; UA: unstable angina; CSA: chronic stable angina.
Age (years)61.2 ± 8.67
Male/female118 (75.6)/38 (24.3)
Hypertension52 (33.4)
Diabetes mellitus37 (23.7)
Dyslipidemia28 (17.9)
Smoking39 (25)
STEMI40 (25.6)
NSTEMI51 (32.7)
UA45 (28.9)
CSA20 (12.8)

 

Table 2. Clinical and Procedural Data of Patients Who Underwent PCI Using Guidezilla Catheter (n = 156)
 
VariableN (%)
PCI: percutaneous coronary intervention; TRI: transradial intervention; TFI: transfemoral intervention; LAD: left anterior descending artery; LCX: left circumflex coronary artery; RCA: right coronary artery; SVG: saphenous vein graft; CTO: chronic total occlusion; PCI: percutaneous coronary intervention; GC: Guidezilla catheter; GEC: Guidezilla extension catheter; BAT: balloon anchoring technique; BLAST: balloon-assisted sliding and tracking.
Success/failure151 (96.7)/5 (3.2)
TRI/TFI54 (34.6)/102 (65.4)
Target vessel
  LAD48 (30.8)
  LCX31 (19.9)
  RCA61 (39.2)
  Multivessel12 (7.6)
  SVG4 (2.5)
Lesion characteristics
  Calcification33 (21.1)
  Tortuosity47 (30.1)
  Angulation29 (18.8)
  Anomalous origin6 (3.8)
  CTO28 (17.9)
  Distally located lesion13 (8.3)
Type of lesion
  B112 (7.7)
  B235 (22.4)
  C109 (69.9)
Mean diameter of the stents3.4 ± 1.2 mm
Mean length of stents34.2 ± 14.4 mm
Mean distance of intubation of GC into the target vessel4.2 ± 1.9 cm
Delivery of GEC catheter
  Aggressive pre-dilatation137 (87.8)
  Cutting balloon modification of the lesion17 (10.9)
  Buddy wire technique15 (9.6)
  BAT47 (30.1)
  BLAST7 (4.5)
Complications (dissection, stent dislodgement)3 (1.9)