Ultrasound-Accelerated Catheter-Directed Thrombolysis

Mrhaf Alsamman, Ali Mohsin Choudhry, Abdulaziz Mheir AlSaadi, Rakesh Prashad


Venous thromboembolism is a very common presentation in the hospital setting. In patients with high-risk pulmonary embolism (PE) or PE and hemodynamic instability, systemic thrombolytic treatment is generally indicated. In those with contraindications to systemic thrombolysis, catheter-directed local thrombolytic therapy and surgical embolectomy are currently considered. In particular, catheter-directed thrombolysis (CDT) is a drug delivery system coupling the endovascular drug administration nearby in the thrombus and the local facilitating effect of ultrasounds. The applications of CDT are currently debated. Here we provide a systematic review of the clinical utilization of CDT.

Cardiol Res. 2023;14(3):161-166
doi: https://doi.org/10.14740/cr1490


Venous thromboembolism; Catheter-directed thrombolysis; Embolectomy; Pulmonary embolism; Deep venous thrombosis

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