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Cardiology Research

John Somberg, MD, Professor Emeritus of Medicine, Cardiology & Pharmacology, Rush University, USA. More...

ISSN-print: 1923-2829  |  ISSN-online: 1923-2837  |  Bimonthly  |  Open Access  |  Aims and Scope

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Combat the COVID-19

Let's Combat COVID-19 Pandemic Together
The COVID-19 outbreak presents the unprecedented challenge for world public and medical practitioners and health care providers. The Elmer Press Inc is herein to participate the combating COVID-19 through all possible efforts, as a clinical medicine publisher, we would facilitate the rapid and effective communication of management of this pandemic, we will consider submissions related to all aspects of this disease, including prevention, basic viral research, epidemiology, treatment, vaccine, fast screening, diagnosis, prognosis, etc. We will process such manuscripts in priority and publish them ASAP after peer-reviewed and accepted.
Collection of COVID-19 articles.


  • Rabies and the Heart

    As one of the neglected diseases, rabies is as a highly fatal viral infection, most prevalent in low- and middle-income regions, which produces a substantial health and economic burden. It mainly affects the central nervous system causing encephalitis, however extraneuronal involvement has been documented. Cardiac structures may be involved and can play a role in the severity of the disease.

  • Effects of Holding Beta-Blockers on the Vital Signs of Heart Failure Patients

    Heart failure with reduced ejection fraction (HFrEF) is associated with recurrent hospitalizations and high mortality. Guideline-directed medical therapy (GDMT) reduces morbidity, mortality and re-admission rates. Despite the evidence, less than 50% of patients with HFrEF are prescribed appropriate medical therapy.

  • Metabolic Syndrome and COVID-19

    Recent studies showed that comorbidities such as diabetes, hypertension and obesity contribute to severe and worse outcomes of coronavirus disease 2019 (COVID-19), suggesting that metabolic syndrome and its components are associated with severity of COVID-19. Here, I systematically reviewed a possible association of metabolic syndrome with the susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and severity of COVID-19 by literature search.

  • Heart Rate Changes Following the Administration of Sugammadex to Infants and Children With Comorbid Cardiac, Cardiovascular, and Congenital Heart Diseases

    Sugammadex is a novel, rapidly-acting pharmacologic agent to reverse steroidal neuromuscular blocking agents with demonstrated advantages over acetylcholinesterase inhibitors. However, anecdotal reports have noted rare instances of bradycardia and even cardiac arrest.

  • Let Us Aggressively Confront the Coronavirus Pandemic

    The coronavirus due to its infectivity, contagious from otherwise healthy appearing individuals and high mortality, poses a serious threat to world health and the world economy. The medical community needs to approach the pandemic with urgency and with approaches that would not ordinarily be taken with a less urgent threat.



Video Report

Therapies for COVID-19: A Disorganized Approach

John Somberg
Over this past year the world has faced a one in a century pandemic that has disrupted people’s lives on a massive scale and the world economy. While vaccines are central to combating the pandemic, alternative therapies will play a part in saving lives and modulating the severity of coronavirus disease 2019 (COVID-19).
Full Text

Early Structural Deterioration of a Sutureless Bioprosthetic Aortic Valve

Michael Cinelli et al. Full Text

Featured Article

Effect of Elevated Left Ventricular End Diastolic Pressure on Instantaneous Wave-Free Ratio and Fractional Flow Reserve Discordance
Instantaneous wave-free ratio (iFR)-guided physiological assessment has been shown to be non-inferior to fractional flow reserve (FFR)-guided assessment for deciding best treatment strategy for angiographically intermediate stenosis. The diagnostic accuracy of iFR compared to FFR reported in various studies is around 80%. Many factors can lead to iFR/FFR discordance, though underlying physiological mechanism of discordance and its associated factors have not been fully evaluated.
Full Text

Image of the Issue

Association of CHA2DS2-VASc Score With Remodeling of Left Atrial Appendage Assessed by Cardiac Computed Tomography
CHA2DS2-VASc score (congestive heart failure; hypertension; ages ≥ 74 years (2 points); diabetes; stroke, transient ischemic attack, or systemic embolism (2 points); vascular disease; ages 65 - 74 years; sex (female)) is a widely used clinical scale to estimate the risk of stroke in patients with non-valvular atrial fibrillation (AF).
Full Text

Current Issue


Vol. 12, No. 2, Apr 2021

Table of Contents


Therapies for COVID-19: A Disorganized Approach Abstract HTML PDF
John Somberg 51-52


Rabies and the Heart Abstract HTML PDF
Bryce Alexander, Jose Patricio Lopez-Lopez, Clara Saldarriaga, Carlos I. Ponte-Negretti, Ricardo Lopez-Santi, Gonzalo Emanuel Perez, Mildren del Sueldo, Fernando Lanas, Kiera Liblik, Adrian Baranchuk 53-59
A Review of the Proposed Mechanistic Actions of Sodium Glucose Cotransporter-2 Inhibitors in the Treatment of Heart Failure Abstract HTML PDF
Brandon Nightingale 60-66
Cardiovascular Health and Disease in the Context of COVID-19 Abstract HTML PDF
Sidhant Umbrajkar, Rachel V. Stankowski, Shereif Rezkalla, Robert A. Kloner 67-79

Original Article

A Retrospective Chart Review of Patients Who Underwent Cardiac Evaluation Before Bariatric Surgery Abstract HTML PDF
Maher Nasser, Evelyn Calderon, Miray Kurtca 80-85
A Dashboard for Tracking Mortality After Cardiac Surgery Using a National Administrative Database Abstract HTML PDF
Katherine J. Greco, Nikhilesh Rao, Richard D. Urman, Ethan Y. Brovman 86-90
Combination of Linagliptin and Empagliflozin Preserves Cardiac Systolic Function in an Ischemia-Reperfusion Injury Mice With Diabetes Mellitus Abstract HTML PDF Suppl1
Akihito Ideishi, Yasunori Suematsu, Kohei Tashiro, Hidetaka Morita, Takashi Kuwano, Sayo Tomita, Kanji Nakai, Shin-ichiro Miura 91-97
Effect of Ezetimibe Added to High-Intensity Statin Therapy on Low-Density Lipoprotein Cholesterol Levels: A Meta-Analysis Abstract HTML PDF Suppl1 Suppl2
Jayden Lee, Ugochukwu Egolum, Harish Parihar, Michael Cooley, Hua Ling 98-108
Platelet-to-Lymphocyte Ratio at Admission as a Predictor of In-Hospital and Long-Term Outcomes in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis Abstract HTML PDF
Herick Alvenus Willim, Joan Carmen Harianto, Harie Cipta 109-116
Effect of Elevated Left Ventricular End Diastolic Pressure on Instantaneous Wave-Free Ratio and Fractional Flow Reserve Discordance Abstract HTML PDF
Hassan Tahir, James Livesay, Benjamin Fogelson, Raj Baljepally 117-125

Short Communication

Association of CHA2DS2-VASc Score With Remodeling of Left Atrial Appendage Assessed by Cardiac Computed Tomography Abstract HTML PDF
Alberto Cecconi, Antonela Sosa Ridolfi, Maria Jose Olivera, Alberto Vera, Susana Hernandez Muniz, Paloma Caballero, Luis Jesus Jimenez-Borreguero, Fernando Alfonso 126-128


Correction to: Evaluation of Index of Cardio-Electrophysiological Balance in Patients With Atrial Fibrillation on Antiarrhythmic-Drug Therapy Abstract HTML PDF
Abdulmecit Afsin, Ramazan Asoglu, Mehmet Ali Kobat, Emin Asoglu, Arif Suner 129

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Cardiology Research, bimonthly, ISSN 1923-2829 (print), 1923-2837 (online), published by Elmer Press Inc.             
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